Estimation of GnRH Pulse Amplitude during Pubertal Development
نویسندگان
چکیده
منابع مشابه
Prenatal androgen excess enhances stimulation of the GNRH pulse in pubertal female rats.
In adolescent girls with polycystic ovary syndrome (PCOS), neuroendocrine derangements manifest after the onset of puberty, characterized by rapid LH pulse frequency. The early mechanism underlying the pubertal regulation of the GNRH/LH pulsatile release in adolescents with PCOS remains uncertain. To determine the effects of prenatal androgen exposure on the activation of GNRH neurons and gener...
متن کاملThe GnRH Pulse Generator
The pulsatile secretion of hormones is an efficient way of coding a large variety of chemical messages. The GnRH pulse pattern determines which gonadotropin is released when and at what concentration, prescribing a detailed set of instructions to the gonads that produce changes in the steroid hormone milieu. Although GnRH neurons possess some inherent rhythmicity, they are diffusely situated wi...
متن کاملGnRH pulse frequency determines LH pulse amplitude by altering the amount of releasable LH in the pituitary glands of ewes.
We have measured the size of the releasable pools of LH and FSH in the pituitary glands of ovariectomized ewes in which the pituitary was isolated surgically from the hypothalamus. The ewes were given GnRH pulses (250 ng) every hour (N = 3) or every 2 h (N = 3) for 1 week and then given a high dose GnRH infusion (0.5 micrograms/min) for 4 h. Blood samples were collected to characterize the LH a...
متن کاملFor Pulse Amplitude
LIU, JIA. Transmitter-based Multiple Access Interference Rejection and Diversity Techniques for Code-division Multiple Access Systems. (Under the direction of Dr. Alexandra Duel-Hallen) For the downlink of direct sequence code-division multiple access (DS-CDMA) systems, transmitter (Tx)-based multiple access interference (MAI) cancellation techniques, termed multiuser precoding, and Tx-based di...
متن کاملThe neurochemistry of the GnRH pulse generator.
We review the crucial role of the two neurotransmitters norepinephrine (NE) and GABA in eliciting GnRH pulse. NE acts via an alpha l-receptor mechanism and also GABA acts at the alpha-subtype of the GABA receptor. The function of NE appears to be induction of phasic activation of GnRH neurons and GABA inhibits GnRH neurons tonically until they are all ready for phasic activation. By an unknown ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1981
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198102000-00015